This calculator is used to estimate glomerular filtration rate (eGFR) using recent formulas for adults of various ethnic backgrounds. For individuals 21 and under, the Schwartz pediatric equation is also included. The GFR estimation is valid only under the assumption of steady state renal function.
This risk score is based on the analysis of 619 biopsy-diagnosed Chinese patients with IgA nephropathy followed for an average of 41.3 months from the time of diagnosis. The calculator uses four baseline clinical variables assessed at the time of biopsy to predict the risk of progression to end stage kidney disease.
Use this calculator to determine an individual's risk of developing IgA nephropathy based on specific genetic markers. The risk score equation is based on the 15 SNPs associated with IgA nephropathy in the analysis of 20,612 individuals from 14 international case-control cohorts of European and Asian ancestry. The risk score is standardized using genotypes of 1,050 individuals from 52 worldwide populations included in the Human Genome Diversity Project (HGDP). This replaces the previous 7 SNP calculator.
From Verbitsky et al. J. Clin Invest 2015 (PMID 25893603) and Verbitsky et al. Nat. Genet 2019 (PMID: 30578417)
This is an expanded list of 625 Mendelian disorders that can involve the kidney and genitourinary tract developed by Hila Rasouly, Emily Groopman and Reuben Heyman-Kantor (7/31/18).
